The VDR gene FokI polymorphism is associated with gestational diabetes mellitus in Turkish women

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Lack of association between FokI polymorphism in vitamin D receptor gene (VDR) & type 2 diabetes mellitus in the Tunisian population

BACKGROUND & OBJECTIVES The impact of several environmental and genetic factors on diabetes is well documented. Though the association between the vitamin D receptor (VDR) gene polymorphisms and type 2 diabetes mellitus (T2DM) has been analyzed in different ethnic groups, the results have been inconsistent. The aim of this study was to evaluate the possible association between VDR FokI polymorp...

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Haptoglobin is associated with Gestational Diabetes Mellitus

The present study aimed at investigating the oxidative stress in patients with Gestational diabetes mellitus (GDM) by estimating Haptoglobin. Blood samples were obtained from 46 GDM pregnant women and 32 controls that were attending the out patient department of M.Y.Hospital, Indore. The lipoprotein profiles, HbA1c and Haptoglobin were measured in all the samples. Significant increase in Haptog...

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Prevalence of gestational diabetes mellitus and associated risk factors in Turkish women: the Trabzon GDM Study

INTRODUCTION The aim of this study was to investigate the prevalence of gestational diabetes mellitus (GDM) in Turkish pregnant women in the Trabzon Region and further to identify population-specific risk factors for GDM. MATERIAL AND METHODS In this prospective cross-sectional survey, universal screening for GDM was performed in 815 pregnant women. Screening was done with a 50-g oral glucose...

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Association of vitamin D receptor gene BsmI (A>G) and FokI (C>T) polymorphism in gestational diabetes among Saudi Women.

OBJECTIVE Vitamin D receptor (VDR) gene polymorphism have a role in diabetes mellitus pathogenesis. Present study was conducted to determine VDR gene variants among Saudi gestational diabetics (GDM) in Madina, KSA. METHODS This cross sectional study was conducted on 112 GDM patients and 218 normal healthy control. Age, body mass index and blood pressure levels were recorded. Serum triglycerid...

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ژورنال

عنوان ژورنال: BMC Medical Genetics

سال: 2019

ISSN: 1471-2350

DOI: 10.1186/s12881-019-0820-0